Young plenary

YP02. V. Cesar – Molecular design of backbone-functionalized N-Heterocyclic Carbenes

Effectenbeurszaal, ground floor July 11, 2017 09:50 - 10:30

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Dr. Vincent César

César, V.; Zhang, Y.; Ruamps, M.; Bastin, S.; Lavigne, G.; Lugan, N.
Laboratoire de Chimie de Coordination du CNRS (UPR 8241)
205 route de Narbonne, BP 44099, 31077 Toulouse Cedex 4, France.

N-Heterocyclic Carbenes (NHCs) are now recognized as ubiquitous and powerful ligands in organometallic chemistry and catalysis as well as excellent organocatalysts.[1] With the aim to unveil new and original features in this area, our group has developed new generations of NHCs, whose common characteristic is the presence of a functionalized heterocyclic backbone. After a short review of the principle and consequences of the ligand design, we will present some selected implementations of the functionalized-backbone NHCs in bond activation,[2] organometallic chemistry[3] and homogeneous catalysis.[4]

[1] Hopkinson M. N., Richter C., Schedler M. and Glorius, F., Nature 510 (2014), 485.
[2] César V., Labat S., Miqueu K., Sotiropoulos J.-M., Brousses R., Lugan N. and Lavigne G., Chem. Eur. J. 19 (2013), 17113.
[3] Recent example: César V., Mallardo V., Nano A., Dahm G., Lugan N., Lavigne G. and Bellemin-Laponnaz S., Chem. Commun. 51 (2015), 5271.
[4] (a) César V., Zhang Y., Kośnik W., Zieliński A., Rajkiewicz A. A., Ruamps M., Bastin S., Lugan N., Lavigne G. and Grela K., Chem. Eur. J. 23 (2017), 1950; (b) Zhang Y., Lavigne G., César V., J. Org. Chem. 80 (2015), 7666; (c) Zhang Y., César V., Storch G., Lugan N. and Lavigne G., Angew. Chem. Int. Ed. 53 (2014), 6482.